Home / Funding Opportunities / 2025 IDD Topical PCORI Funding Announcement

2025 Intellectual and Developmental Disabilities Topical PCORI Funding Announcement

Photo: Clinician performing an exam on a patient with Down Syndrome. PCORI’s Online System opened on April 1 for submissions of Letters of Intent (LOI) for the Cycle 2 2025 Intellectual and Developmental Disabilities Topical PCORI Funding Announcement (PFA).

This PFA seeks to fund study proposals that focus on people with intellectual and developmental disabilities (IDDs). Compared to people without IDD, a higher proportion of people with IDD have co-occurring physical and mental health conditions and unmet healthcare needs.

This opportunity aims to fund the comparison of interventions encountered by individuals of all ages who have IDD. Comparisons can be clinical interventions or systems approaches and can include pharmacological or non-pharmacological interventions.

PCORI is particularly interested in proposals that address one of the following Special Areas of Emphasis:

  • Oral Health
  • Gastrointestinal Health
  • Improving Care Delivery

This funding announcement will accept applications with direct costs up to $12 million dollars and up to five years in duration.

Photo: Three month old Trisomy 18 infant with a nasogastric feeding tube.